Phosphopyruvate hydratase
Web[5] [6] Gamma-enolase is a phosphopyruvate hydratase . Gamma-enolase is one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates. [5] Web14-3-2-protein, 2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming), 2-phospho-D-glycerate hydro-lyase activity, 2-phospho-D-glycerate-hydrolase activity, 2 …
Phosphopyruvate hydratase
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WebPhosphoenolpyruvate ( 2-phosphoenolpyruvate, PEP) is the ester derived from the enol of pyruvate and phosphate. It exists as an anion. PEP is an important intermediate in biochemistry. It has the highest-energy phosphate bond found (−61.9 kJ/mol) in organisms, and is involved in glycolysis and gluconeogenesis.
WebAn enzyme catalyzing the reversible dehydration of 2-phospho-d-glycerate to phosphoenolpyruvate and water; a step in both glycolysis and gluconeogenesis; several … WebPhosphopyruvate Hydratase / metabolism Rats S100 Proteins / immunology Substances Antibodies, Monoclonal Indicators and Reagents Isoenzymes Nerve Tissue Proteins S100 …
WebChildren of phosphopyruvate hydratase activity (GO:0004634) EC 4.2.1.11 MetaCyc 2PGADEHYDRAT-RXN Reactome R-HSA-71660 R-HSA-70494 RHEA 10164 Cite this data• … Web肺癌是全球常见恶性肿瘤,发病率占第二位,病死率占第一位,预后极差,小细胞肺癌(small cell lung cancer,SCLC)是肺癌一种,源于神经内分泌细胞及支气管黏膜干细胞,患病率占肺癌患者15%~25% [1] 。 依托泊苷联合顺铂(EP)方案化疗是治疗SCLC的标准治疗方案,相比于其他类型肿瘤,SCLC初治化疗 ...
WebTo validate the proteins identified by 2-DE and MALDI-TOF/TOF mass spectrometry further, the expression of genes for arginine kinase, phosphopyruvate hydratase, and actin …
WebJun 30, 2024 · Among these eight proteins, phosphopyruvate hydratase was a prevalent IgE-binding protein among these Chinese patients with binding observed in 100% of sera. Moreover, 13 peptides were predicted as epitopes of phosphopyruvate hydratase. chubb littleton roadPhosphopyruvate hydratase, usually known as enolase, is a metalloenzyme (EC 4.2.1.11) that catalyses the conversion of 2-phosphoglycerate (2-PG) to phosphoenolpyruvate (PEP), the ninth and penultimate step of glycolysis. The chemical reaction is: 2-phospho-D-glycerate See more In humans there are three subunits of enolase, α, β, and γ, each encoded by a separate gene that can combine to form five different isoenzymes: αα, αβ, αγ, ββ, and γγ. Three of these isoenzymes (all homodimers) are … See more Using isotopic probes, the overall mechanism for converting 2-PG to PEP is proposed to be an E1cB elimination reaction involving … See more Small-molecule inhibitors of enolase have been synthesized as chemical probes (substrate-analogues) of the catalytic mechanism of the … See more • Enolase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) See more Enolase is a member of the large enolase superfamily. It has a molecular weight of 82,000-100,000 Daltons depending on the isoform. In human alpha enolase, the two subunits are antiparallel in orientation so that Glu of one subunit forms an ionic bond with See more In recent medical experiments, enolase concentrations have been sampled in an attempt to diagnose certain conditions and their severity. For example, higher concentrations of … See more • Holt A, Wold F (December 1961). "The isolation and characterization of rabbit muscle enolase". The Journal of Biological Chemistry. 236 (12): 3227–3231. doi:10.1016/S0021-9258(18)94000-7. PMID 13908561. • Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), … See more chubb lloyds insurance company dallas texasWebPhosphopyruvate Hydratase / metabolism Rats S100 Proteins / immunology Substances Antibodies, Monoclonal Indicators and Reagents Isoenzymes Nerve Tissue Proteins S100 Proteins ... design and arts craftsWebNational Center for Biotechnology Information design and build a small business networkWebThe PEC antifouling immunosensor based on ZnO/CdSe has a wide linear range (0.10 pg mL -1 -100 ng mL -1) and a low detection limit (34 fg mL -1 ), which has potential application in the clinical diagnosis of small cell lung cancer. MeSH terms Biofouling* / prevention & control Biosensing Techniques* Cadmium Compounds* Electrochemical Techniques chubb limited tickerWebPDF 0.1 MB. Enolase (phosphopyruvate hydratase) is a metalloenzyme responsible for the catalysis of the conversion of 2-phosphoglycerate (2-PG) tophosphoenolpyruvate (PEP), … chubb locks custodialWebphosphoenolpyruvate CHEBI:58702 zoom Cofactor Protein has 1 cofactor binding site: Mg2+ ( UniProtKB Rhea CHEBI:18420 ) Note: Mg 2+ is required for catalysis and for stabilizing the dimer. Pathway Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5. Features Showing features for binding site, active … design and build architects london